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Congo Ebola outbreak becomes second largest ever recorded

The Bundibugyo Ebola outbreak in the Democratic Republic of the Congo (DRC) has become the second largest ever recorded, surpassed only by the 2014 to 2016 West Africa epidemic and its 28,616 confirmed, probable and suspected cases. According to the World Health Organization (WHO) Disease Outbreak News, with data as of July 30, the country has reported 3,605 confirmed cases and 1,587 deaths, a crude case fatality ratio (CFR) of 44 percent. It is now the largest Ebola outbreak ever reported in the DRC, passing the 2018 to 2020 Kivu epidemic’s total of 3,470 cases in 76 days. Kivu took 23 months.

It spans 49 of 140 health zones across Ituri, North Kivu, South Kivu, Haut-Uele and Tshopo. Epidemiological week 30 was the worst yet, with 567 cases and 296 deaths, roughly 42 deaths a day. Dr. Thierno Baldé, the WHO incident manager, said Ituri accounts for more than 90 percent of cases and roughly 80 percent of deaths. Uganda declared its own outbreak over on July 28, having recorded no confirmed case since June 21, at 20 cases and two deaths, a fatality rate of about 10 percent.

WHO map of Ebola-affected health zones in eastern Democratic Republic of the Congo [Photo: WHO]

The confirmed tally is a floor. Placide Mbala-Kingebeni of the National Institute of Biomedical Research has said the outbreak was building for months before detection and that health zones remain unreachable because of insecurity. WHO modeling puts true infections at two to four times the confirmed count. Doctors Without Borders reports that because Bundibugyo virus disease is rare, manufacturers do not routinely produce enough specialized test kits, leaving hundreds of samples untested.

Contact tracing has gone backwards. As of July 28, 78.3 percent of identified contacts were under follow-up, down from 82 percent in mid-July, against a WHO target of 90 to 95 percent cited by Dr. Abdi Mahamud. That figure counts only the people the system already knows about. The Africa Centers for Disease Control and Prevention (Africa CDC) estimates that fewer than 9 percent of the contacts that ought to be traced are monitored at all. Roughly 80 percent of new confirmed cases appear outside any known transmission chain, Jon Cohen reported in Science, and the WHO has said, as reported in STAT, that two-thirds of confirmed deaths never sought care and were tested only after death.

The case fatality ratio has tracked that failure. It stood at about 23 percent in mid-June, 25.9 percent on June 19, 31.0 percent on July 1, 39.0 percent on July 15 and 44.0 percent on July 30. The two previous Bundibugyo outbreaks recorded 25 to 40 percent. The virus has not changed in six weeks. What the rising ratio records is a response reaching people later and later, capturing the dying while mild and moderate infections pass through undetected.

The trajectory was modeled in advance. On June 5, Eric Q. Mooring and colleagues published “Modeled Scenario Projections for the Ebola Disease Outbreak Caused by Bundibugyo Virus, 2026” in the Morbidity and Mortality Weekly Report. Their branching-process model, calibrated to death counts as of May 24, when roughly 50 had been reported, placed the probable spillover in mid to late February, three months before the outbreak was declared on May 15.

The model ran four scenarios turning on one variable: the share of symptomatic patients found, isolated and treated before infecting anyone else. Under poor isolation, set at 20 percent, it projected a 65 percent likelihood of more than 20,000 cases within three months alongside more than 2,000 deaths. Under high isolation at 70 percent, about one in 20 simulations exceeded 10,000 cases. Jason Asher of the Centers for Disease Control and Prevention (CDC) Center for Forecasting and Outbreak Analytics called the work a planning tool rather than a forecast.

Two months on, the response is operating at or below the poor branch, and the projection has held. Confirmed deaths stood at 1,587 on July 30, against a worst-case scenario of more than 2,000 within three months of May 24. That figure counts only the laboratory-confirmed dead.

DR Congo Ebola 2026: confirmed cases and deaths, with projections [Photo: WHO]

On cases the arithmetic requires care. The model counted all infections, not laboratory-confirmed ones, and 3,605 is far short of 20,000. But the WHO’s own multiplier implies between 7,200 and 14,400 infections as of July 30, which places the outbreak inside the worst-case band. The CDC wrote on June 5 that this was already the largest known Bundibugyo outbreak and could become one of the largest Ebola epidemics on record. The confirmed toll then stood in the hundreds.

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